Article
[The effect of GST M1 and GST T1 gene mutations on anti-tuberculous drug induced hepatic injury].
Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases - 1 Apr 2009
Guo Mei, Sun Yong-Hong, Li Shi-Ming, Wang Dong, Liu Qian, Zhang Xi-Ying, Liu Xiao-Xiao, Feng Fu-Min
Abstract excerpt
OBJECTIVE: To study the relationship between the polymorphisms of GST M1 and GST T1 genes and anti-tuberculous drug induced hepatic injury (ADIH). METHODS: A 1:1 matched case-control study was carried out. One hundred and six patients [age (49 +/- 19) years, 73 men and 33 women] fulfilling the criteria of ADIH during the 3 month follow-up after the initiation of anti-tuberculous therapy were included, while 106...
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