Article
A prospective observational study to evaluate Glutathione S-transferase gene polymorphism and its association with Antitubercular drugs induced liver injury in tertiary hospital.
The Indian journal of tuberculosis - 1 Jul 2022
Akhtar Javed, Singh Sarvesh, Verma Ajay Kumar, Pal Rishi, Nath Rajendra
Abstract excerpt
BACKGROUND: Anti-TB drugs are most common cause of idiosyncratic hepatotoxicity worldwide. Reactive metabolite formed during drug metabolism has been involved in a clinical toxicity are described as 'idiosyncratic' drug induce liver injury (DILI). We have observed the distribution of glutathione S -transferase (GST) gene polymorphism & its association with drug-induced liver injury in patients taking...
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