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Article

[Relationship between the polymorphisms of UGT1A6 genes and anti-tuberculosis drug induced hepatic-injury].

Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology - 1 Mar 2011

Hao Jin-qi, Chen Yi, Li Shi-ming, Zhang Peng, Yu Yan-qin, Tang Gui-yu, Feng Fu-min

Abstract excerpt

OBJECTIVE: To investigate the relationship between the polymorphisms of UGT1A6 genes and anti-tuberculosis drug induced hepatic-injury (ADIH). METHODS: 202 cases and 239 controls were collected and a case-control study was conducted. Information on related risk factors of tuberculosis was collected. The genotypes of UGT1A6-19T/G, UGT1A6-308C/A and UGT1A6-541A/G genetic polymorphisms were detected by polymerase...

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Antitubercular Agents
Case-Control Studies
Chemical and Drug Induced Liver Injury
Glucuronosyltransferase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Genetic

Tuberculosis, Pulmonary

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PMID: 21586239
DOI: 10.3760/cma.j.issn.1007-3418.2011.03.012

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