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Article

Regulatory effect of common promoter polymorphisms on the expression of the 11beta-hydroxysteroid dehydrogenase type 1 gene.

Hormone research - 1 Jan 2009

Ku Yun Hyi, Koo Bo Kyung, Kwak Soo Heon, Cho Young Min, Shin Hyoung Doo, Lee Hong Kyu, Kim Yeonjung, Choi Jung-Won, Oh Bermseok, Park Kyong Soo

Abstract excerpt

BACKGROUND/AIMS: Glucocorticoids play an important role in the pathogenesis of obesity and insulin resistance. 11beta-hydroxysteroid dehydrogenase type 1 (HSD11B1), which converts inactive cortisone to active cortisol, has become an emerging therapeutic target for type 2 diabetes mellitus and obesity. In this study, we examined the association between HSD11B1 polymorphisms and type 2 diabetes and metabolic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19571556
DOI: 10.1159/000224337

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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