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Association study of 11beta-hydroxysteroid dehydrogenase type 1 gene polymorphisms and metabolic syndrome in urban Japanese cohort.

Diabetes research and clinical practice - 1 Aug 2009

Miyamoto Yoshihiro, Morisaki Hiroko, Yamanaka Itaru, Kokubo Yoshihiro, Masuzaki Hiroaki, Okayama Akira, Tomoike Hitonobu, Nakao Kazuwa, Okamura Tomonori, Yoshimasa Yasunao, Morisaki Takayuki

Abstract excerpt

11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1), one of the isoforms of the 11beta-hydroxysteroid dehydrogenase enzymes, acts as an oxo-reductase to reactivate cortisone to cortisol, plays a critical role in tissue-specific corticosteroid reactions, and is therefore a key molecule associated with the development of metabolic syndrome. We investigated whether variations in the 11beta-HSD1 gene correlated...

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PMID: 19535162
DOI: 10.1016/j.diabres.2009.05.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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