Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Inter-individual variation in flavin-containing monooxygenase 3 in livers from Japanese: correlation with hepatic transcription factors.

Drug metabolism and pharmacokinetics - 1 Jan 2009

Nagashima Satomi, Shimizu Makiko, Yano Hiroshi, Murayama Norie, Kumai Toshio, Kobayashi Shinichi, Guengerich F Peter, Yamazaki Hiroshi

Abstract excerpt

Human flavin-containing monooxygenase 3 (FMO3)-mediated microsomal oxygenation activity, levels of FMO3 protein and FMO3 mRNA and modifications were investigated in Japanese livers genotyped for the FMO3 gene. Significant correlations were observed for benzydamine N-oxygenation or methyl p-tolyl sulfide S-oxygenation activity (in the range of approximately 20- to approximately 40-fold) and FMO3 levels determined...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Benzodiazepines
Share to CCAAT-Binding Factor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatocyte Nuclear Factor 4

Share to Microsomes, Liver

Share to Olanzapine

Share to Osmolar Concentration

Share to Oxygenases

Share to Sulfides

Source

Open in PubMed Open full text

Identifiers

PMID: 19571433
DOI: 10.2133/dmpk.24.218
PMCID: PMC4755719

Genes

FMO3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Inter-individual variation in flavin-containing monooxygenase 3 in livers from Japanese: correlation with hepatic transcription factors.PMID 19571433Read ↗

Genetic and Nongenetic Factors Associated with Protein Abundance of Flavin-Containing Monooxygenase 3 in Human Liver.Semantic proximity Read ↗

Human Hepatic Flavin-Containing Monooxygenases 1 (FMO1) and 3 (FMO3) Developmental ExpressionSemantic proximity Read ↗

Interindividual differences of human flavin-containing monooxygenase 3: genetic polymorphisms and functional variation.Semantic proximity Read ↗

Survey of variants of human flavin-containing monooxygenase 3 (FMO3) and their drug oxidation activities.Semantic proximity Read ↗

Discovery of novel flavin-containing monooxygenase 3 (FMO3) single nucleotide polymorphisms and functional analysis of upstream haplotype variants.Semantic proximity Read ↗

Human flavin-containing monooxygenase (form 3): polymorphisms and variations in chemical metabolism.Semantic proximity Read ↗

Identification and functional analysis of common human flavin-containing monooxygenase 3 genetic variants.Semantic proximity Read ↗

Flavin-containing monooxygenase 3 gene polymorphisms in Turkish population.Semantic proximity Read ↗

Variants in the flavin-containing monooxygenase 3 (FMO3) gene responsible for trimethylaminuria in a Japanese population.Semantic proximity Read ↗

Regulation of flavin-containing mono-oxygenase ( <i>Fmo3</i> ) gene expression by steroids in mice and humansSemantic proximity Read ↗

Effect of genetic variants of the human flavin-containing monooxygenase 3 on N- and S-oxygenation activities.Semantic proximity Read ↗

Flavin-containing monooxygenase 3 and human disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.