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Article

Interindividual differences of human flavin-containing monooxygenase 3: genetic polymorphisms and functional variation.

Drug metabolism and disposition: the biological fate of chemicals - 1 Oct 2002

Cashman John R, Zhang Jun

Abstract excerpt

The human flavin-containing monooxygenase (form 3) (FMO3) participates in the oxygenation of nucleophilic heteroatom-containing drugs, xenobiotics, and endogenous materials. Currently, six forms of the FMO gene are known, but it is FMO3 that is the major form in adult human liver that is likely responsible for the majority of FMO-mediated metabolism. The substrate structural feature requirements for human FMO3 is...

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Source

Identifiers

PMID: 12228178
DOI: 10.1124/dmd.30.10.1043

Genes

FMO3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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