Article
Regulation of flavin-containing mono-oxygenase ( <i>Fmo3</i> ) gene expression by steroids in mice and humans
1 Dec 2014
Abstract excerpt
Abstract Flavin-containing mono-oxygenases (FMOs) are a family of microsomal chemical- and drug-metabolizing enzymes. FMO3 is a major FMO form in adult mouse and human liver. FMO3 mutations have been associated with the incidence and severity of trimethylaminuria (TMAU), a metabolic disorder characterized by the inability of the affected individual to metabolize the odorous trimethylamine to its non-odorous...
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