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Article

TWIK-1 and TREK-1 are potassium channels contributing significantly to astrocyte passive conductance in rat hippocampal slices.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Jul 2009

Zhou Min, Xu Guangjin, Xie Minjie, Zhang Xuexin, Schools Gary P, Ma Liqun, Kimelberg Harold K, Chen Haijun

Abstract excerpt

Expression of a linear current-voltage (I-V) relationship (passive) K(+) membrane conductance is a hallmark of mature hippocampal astrocytes. However, the molecular identifications of the K(+) channels underlying this passive conductance remain unknown. We provide the following evidence supporting significant contribution of the two-pore domain K(+) channel (K(2P)) isoforms, TWIK-1 and TREK-1, to this...

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Identifiers

PMID: 19571146
DOI: 10.1523/JNEUROSCI.5784-08.2009
PMCID: PMC6665656

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GFAP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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