Article
Molecular and functional characterization of an Na+-independent choline transporter in rat astrocytes.
Journal of neurochemistry - 1 Sept 2005
Inazu Masato, Takeda Hiroshi, Matsumiya Teruhiko
Abstract excerpt
In this study, we examined the molecular and functional characterization of choline uptake into cultured rat cortical astrocytes. Choline uptake into astrocytes showed little dependence on extracellular Na+. Na+-independent choline uptake was saturable and mediated by a single transport system, with an apparent Michaelis-Menten constant (Km) of 35.7 +/- 4.1 microm and a maximal velocity (Vmax) of 49.1 +/- 2.0...
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