Article

Astrocytic Gapjinc (TMEM43) modulates gap junction networks by facilitating transjunctional potentials

2022-11-09

Abstract excerpt

The TMEM43 gene has been reported to play supportive but critical roles in human diseases including cancer, arrhythmogenic right ventricular cardiomyopathy (ARVC), and auditory neuropathy spectrum disorder (ANSD). However, direct characterization of the TMEM43 protein itself and its role in the brain remain unexplored. In this study, we demonstrated that TMEM43 confers ion channel activities via the lipid bilayer...

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Literature Corpus work: ccb76102-046f-5985-b948-eb010e58e462
DOI: 10.1101/2022.11.08.515259

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