Article
Origin of expression of the herpes simplex virus type 1 protein U(S)1.5.
Journal of virology - 1 Sept 2009
Bowman J Jason, Schaffer Priscilla A
Abstract excerpt
ICP22, an immediate-early protein of herpes simplex virus type 1 (HSV-1), is required for viral replication in nonpermissive cell types and for expression of a class of late viral proteins which includes glycoprotein C. An understanding of the mechanism of ICP22 function has been complicated by the coexpression of the full-length protein with an in-frame, C-terminus-specific protein, U(S)1.5. In this report, we...
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