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Article

Association of genetic variants rs641153 (CFB), rs2230199 (C3), and rs1410996 (CFH) with age-related macular degeneration in a Brazilian population.

Experimental biology and medicine (Maywood, N.J.) - 1 Nov 2021

Neto Jamil M, Viturino Marina Gm, Ananina Galina, Bajano Flávia F, Costa Sueli M da S, Roque Alicia B, Borges Gessica Fs, Franchi Raissa, Rim Priscila Hh, Medina Flávio M, Costa Fernando F, Melo Mônica B de, de Vasconcellos José Pc

Abstract excerpt

This study aimed to investigate the association among genetic variants of the complement pathway CFB R32Q (rs641153), C3 R102G (rs2230199), and CFH (rs1410996) with age-related macular degeneration (AMD) in a sample of the Brazilian population. In a case-control study, 484 AMD patients were classified according to the clinical age-related maculopathy grading system (CARMS) and compared to 479 unrelated controls....

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Source

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Identifiers

PMID: 34233521
DOI: 10.1177/15353702211024543
PMCID: PMC8581831

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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