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Article

microRNA miR-196a-2 and breast cancer: a genetic and epigenetic association study and functional analysis.

Cancer research - 15 Jul 2009

Hoffman Aaron E, Zheng Tongzhang, Yi Chunhui, Leaderer Derek, Weidhaas Joanne, Slack Frank, Zhang Yawei, Paranjape Trupti, Zhu Yong

Abstract excerpt

Increasing evidence has suggested that microRNAs (miRNA) play an important role in tumorigenesis. As transcriptional regulators, altered miRNA expression may affect many cancer-related biological pathways, indicating that miRNAs can function as tumor suppressors and/or oncogenes. We first performed a genetic association analysis by screening genetic variants in 15 miRNA genes and detected that a common sequence...

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Identifiers

PMID: 19567675
DOI: 10.1158/0008-5472.CAN-09-0236
PMCID: PMC2716085

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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