Article
Mature microRNA sequence polymorphism in MIR196A2 is associated with risk and prognosis of head and neck cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Jul 2010
Christensen Brock C, Avissar-Whiting Michele, Ouellet Lauren G, Butler Rondi A, Nelson Heather H, McClean Michael D, Marsit Carmen J, Kelsey Karl T
Abstract excerpt
PURPOSE: The central role of microRNAs as regulators of translation has been well established, whereas the relationships between genetic variation in microRNAs and disease risk is only beginning to be explored. A polymorphism in the MIR196A2 locus has shown associations with lung, breast, esophageal, and gastric tumors but has not been examined in head and neck cancers, which share similar pathology and etiology...
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