Article
Evaluation of single nucleotide polymorphisms in microRNAs (hsa-miR-196a2 rs11614913 C/T) from Brazilian women with breast cancer.
BMC medical genetics - 10 Dec 2012
Linhares José Juvenal, Azevedo Marcos, Siufi Adalberto Abraão, de Carvalho Cristina Valleta, Wolgien Maria Del Carmen Garcia Molina, Noronha Emmanuelle Coelho, Bonetti Tatiana Carvalho de Souza, da Silva Ismael Dale Cotrim Guerreiro
Abstract excerpt
BACKGROUND: Emerging evidence has shown that miRNAs are involved in human carcinogenesis as tumor suppressors or oncogenes. Single nucleotide polymorphisms (SNPs) located in pre-miRNAs may affect the processing and therefore, influence the expression of mature miRNAs. Previous studies generated conflicting results when reporting association between the hsa-miR-196a2 rs11614913 common polymorphism and breast...
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