Article
Hsa-miR-196a2 Rs11614913 polymorphism contributes to cancer susceptibility: evidence from 15 case-control studies.
PloS one - 31 Mar 2011
Chu Haiyan, Wang Meilin, Shi Danni, Ma Lan, Zhang Zhizhong, Tong Na, Huo Xinying, Wang Wei, Luo Dewei, Gao Yan, Zhang Zhengdong
Abstract excerpt
BACKGROUND: MicroRNAs (miRNAs) are a family of endogenous, small and noncoding RNAs that negatively regulate gene expression by suppressing translation or degrading mRNAs. Recently, many studies investigated the association between hsa-miR-196a2 rs11614913 polymorphism and cancer risk, which showed inconclusive results. METHODOLOGY/PRINCIPAL FINDINGS: We conducted a meta-analysis of 15 studies that included 9,341...
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