Somatic Mutation of the SNP rs11614913 and Its Association with Increased MIR 196A2 Expression in Breast Cancer.

doi:10.1089/dna.2014.2785

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Somatic Mutation of the SNP rs11614913 and Its Association with Increased MIR 196A2 Expression in Breast Cancer.

DNA and cell biology - 1 Feb 2016

Zhao Huanhuan, Xu Jingman, Zhao Dan, Geng Meijuan, Ge Haize, Fu Li, Zhu Zhengmao

Abstract excerpt

Common genetic variants (single-nucleotide polymorphisms [SNPs]) in microRNA genes may alter their maturation or expression, resulting in varied functional consequences. Several studies have evaluated the association between the SNP rs11614913 and cancer risk in diverse populations and in a range of cancers, with contradictory outcomes. In this study, we examined 114 paired samples (tumor and normal tissues) from...

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PMID: 26710106
DOI: 10.1089/dna.2014.2785

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