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Article

Large-scale analysis of chromosomal aberrations in uterine leiomyoma.

American journal of obstetrics and gynecology - 1 May 2026

Ilves Sini, Jokinen Vilja, Katainen Riku, Siili Emma, Bützow Ralf, Heikinheimo Oskari, Pasanen Annukka, Karhu Auli, Välimäki Niko, Aaltonen Lauri A

Abstract excerpt

BACKGROUND: Chromosomal aberrations in tumors are key indicators of genomic instability and important drivers of neoplasia. While chromosomal changes in uterine leiomyomas have been studied for decades, comprehensive evaluation of chromosomal aberrations in uterine leiomyomas on the scale of modern tumor research has been lacking. OBJECTIVE: To comprehensively characterize somatic chromosomal aberrations in...

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Topics

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Share to Chromosome Aberrations
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fumarate Hydratase

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Share to Polymorphism, Single Nucleotide

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Source

Identifiers

PMID: 41548634
DOI: 10.1016/j.ajog.2026.01.010

Genes

HMGA1
HMGA2
PLAG1
COL4A5
FH
MED12
YEATS4
CDKN2C

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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