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Article

Highly heterogeneous genomic landscape of uterine leiomyomas by whole exome sequencing and genome-wide arrays.

Fertility and sterility - 1 Feb 2017

Yatsenko Svetlana A, Mittal Priya, Wood-Trageser Michelle A, Jones Mirka W, Surti Urvashi, Edwards Robert P, Sood Anil K, Rajkovic Aleksandar

Abstract excerpt

OBJECTIVE: To determine the genomic signatures of human uterine leiomyomas and prevalence of MED12 mutations in human uterine leiomyosarcomas. DESIGN: Retrospective cohort study. SETTING: Not applicable. PATIENT(S): This study included a set of 16 fresh frozen leiomyoma and corresponding unaffected myometrium specimens as well as 153 leiomyosarcomas collected from women diagnosed with uterine leiomyomas or...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27889101
DOI: 10.1016/j.fertnstert.2016.10.035

Genes

MED12
ADAM18
AHR
CAPRIN1
CDK8
DCN
HUWE1
MED18
MED8
NRG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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