Molecular differential diagnosis of uterine leiomyomas and leiomyosarcomas.

doi:10.1093/biolre/ioy195

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Article

Molecular differential diagnosis of uterine leiomyomas and leiomyosarcomas.

Biology of reproduction - 24 Dec 2019

Mas Aymara, Simón Carlos

Abstract excerpt

Uterine leiomyomas (LM) and leiomyosarcomas (LMS) are considered biologically unrelated tumors due to their cytogenetic and molecular disparity. Yet, these tumors share morphological and molecular characteristics that cannot be differentiated through current clinical diagnostic tests, and thus cannot be definitively classified as benign or malignant until surgery. Newer approaches are needed for the...

Topics

Circulating Tumor DNA
Diagnosis, Differential
Female
High-Throughput Nucleotide Sequencing
Humans
Leiomyoma
Leiomyosarcoma
Liquid Biopsy
Molecular Diagnostic Techniques
Mutation
Precision Medicine
Uterine Neoplasms

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Open in PubMed

Identifiers

PMID: 30184111
DOI: 10.1093/biolre/ioy195

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