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Article

Association of molecular markers in Plasmodium falciparum crt and mdr1 with in vitro chloroquine resistance: a Philippine study.

Parasitology international - 1 Jun 2009

Hatabu Toshimitsu, Iwagami Moritoshi, Kawazu Shin-ichiro, Taguchi Nao, Escueta Aleyla D, Villacorte Elena A, Rivera Pilarita T, Kano Shigeyuki

Abstract excerpt

Specific mutations in the pfcrt and pfmdr1 genes have been reported to be associated with chloroquine-resistant falciparum malaria parasites worldwide. These genetic markers are considered to be useful tools for the elucidation of several aspects of the epidemiology of drug resistant malaria. In this study, Plasmodium falciparum isolates from three distinct areas of the Philippines were analyzed for...

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PMID: 19567229
DOI: 10.1016/j.parint.2009.01.010

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