Association of molecular markers in Plasmodium falciparum crt and mdr1 with in vitro chloroquine resistance: a Philippine study.

doi:10.1016/j.parint.2009.01.010

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Article

Association of molecular markers in Plasmodium falciparum crt and mdr1 with in vitro chloroquine resistance: a Philippine study.

Parasitology international - 1 Jun 2009

Hatabu Toshimitsu, Iwagami Moritoshi, Kawazu Shin-ichiro, Taguchi Nao, Escueta Aleyla D, Villacorte Elena A, Rivera Pilarita T, Kano Shigeyuki

Abstract excerpt

Specific mutations in the pfcrt and pfmdr1 genes have been reported to be associated with chloroquine-resistant falciparum malaria parasites worldwide. These genetic markers are considered to be useful tools for the elucidation of several aspects of the epidemiology of drug resistant malaria. In...

Topics

Antimalarials
Chloroquine
Drug Resistance
Genetic Markers
Humans
Malaria, Falciparum
Membrane Transport Proteins
Multidrug Resistance-Associated Proteins
Mutation
Parasitic Sensitivity Tests
Philippines
Plasmodium falciparum
Protozoan Proteins

Source

Open in PubMed

Identifiers

PMID: 19567229
DOI: 10.1016/j.parint.2009.01.010

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-19567229-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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