Article
Association of pfcrt but not pfmdr1 alleles with chloroquine resistance in Iranian isolates of Plasmodium falciparum.
The American journal of tropical medicine and hygiene - 1 Apr 2008
Zakeri Sedigheh, Afsharpad Mandana, Kazemzadeh Tahmineh, Mehdizadeh Kambiz, Shabani Ashraf, Djadid Navid Dinparast
Abstract excerpt
This study was designed to analyze the Plasmodium falciparum chloroquine resistance transporter (pfcrt) and P. falciparum multidrug resistance 1 (pfmdr1) mutations as markers of chloroquine (CQ) resistance in 200 blood samples collected from malaria patients in south-eastern Iran during 2002-2005. Among these, 25 (post-treatment) fulfilled the 28-day follow-up study. A high number of Iranian P. falciparum (97%)...
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