Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pfcrt mutant haplotypes may not correspond with chloroquine resistance.

Journal of infection in developing countries - 11 Jun 2014

Goswami Diganta, Dhiman Sunil, Rabha Bipul, Kumar Dinesh, Baruah Indra, Sharma Dhirendra Kumar, Veer Vijay

Abstract excerpt

INTRODUCTION: Chloroquine resistance in Plasmodium falciparum is associated with mutations in pfcrt and pfmdr1 genes. The frequency distribution of pfcrt K76T and pfmdr1 N86Y mutations and their association with chloroquine susceptibility was studied in an endemic area along the Indo-Bangladesh border. METHODOLOGY: A single-arm prospective study of clinical and parasitological responses in P. falciparum malaria...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genes, Protozoan
Share to Malaria, Falciparum

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Antimalarials

Share to Chloroquine

Share to Developing Countries

Share to Multidrug Resistance-Associated Proteins

Share to Plasmodium falciparum

Share to Protozoan Proteins

Source

Identifiers

PMID: 24916876
DOI: 10.3855/jidc.3398

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pfcrt mutant haplotypes may not correspond with chloroquine resistance.PMID 24916876Read ↗

Mutant pfcrt "SVMNT" haplotype and wild type pfmdr1 "N86" are endemic in Plasmodium vivax dominated areas of India under high chloroquine exposureSemantic proximity Read ↗

Association of pfcrt but not pfmdr1 alleles with chloroquine resistance in Iranian isolates of Plasmodium falciparum.Semantic proximity Read ↗

Chloroquine resistance in Plasmodium falciparum malaria parasites conferred by pfcrt mutations.Semantic proximity Read ↗

Sequence analysis of pfcrt and pfmdr1 genes and its association with chloroquine resistance in Southeast Indian Plasmodium falciparum isolatesSemantic proximity Read ↗

Large-scale survey for novel genotypes of Plasmodium falciparum chloroquine-resistance gene pfcrt.Semantic proximity Read ↗

Plasmodium falciparum genotypes associated with chloroquine and amodiaquine resistance in Guinea-Bissau.Semantic proximity Read ↗

Polymorphisms in the<i>Plasmodium falciparum pfcrt</i>and<i>pfmdr‐1</i>Genes and Clinical Response to Chloroquine in Kampala, UgandaSemantic proximity Read ↗

Dynamics of pfcrt alleles CVMNK and CVIET in chloroquine-treated Sudanese patients infected with Plasmodium falciparum.Semantic proximity Read ↗

Prevalence of the K76T mutation in the pfcrt gene of Plasmodium falciparum among chloroquine responders in IndiaSemantic proximity Read ↗

Chloroquine resistant P. falciparum prevalence is low and unchanged between 1990 and 2005 in Guinea-Bissau: an effect of high chloroquine dosage?Semantic proximity Read ↗

Persistence of chloroquine-resistant haplotypes of Plasmodium falciparum in children with uncomplicated Malaria in Lagos, Nigeria, four years after change of chloroquine as first-line antimalarial medicineSemantic proximity Read ↗

Association between prevalence of chloroquine resistance and unusual mutation in pfmdr-I and pfcrt genes in India.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.