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Article

Maternal influence of prolyl endopeptidase on fat mass of adult progeny.

International journal of obesity (2005) - 1 Sept 2009

Warden C H, Fisler J S, Espinal G, Graham J, Havel P J, Perroud B

Abstract excerpt

BACKGROUND: Maternal genotype has lifetime effects on progeny, but few specific genes, and no proteases, are known to underlie maternal effects. Prolyl endopeptidase (PREP) is a serine protease with putative substrates that regulate appetite or milk production. OBJECTIVE: To test effects of PREP on obesity phenotypes in mice. DESIGN: Mice with a gene trap (GT) of PREP (PREP(gt/gt)) on the C57BL/6J (B6) background...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19564876
DOI: 10.1038/ijo.2009.129
PMCID: PMC2743752

Genes

PREP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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