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Article

Influence of abnormally high leptin levels during pregnancy on metabolic phenotypes in progeny mice.

American journal of physiology. Regulatory, integrative and comparative physiology - 1 Dec 2013

Makarova Elena N, Chepeleva Elena V, Panchenko Polina E, Bazhan Nadezhda M

Abstract excerpt

Maternal obesity increases the risk of obesity in offspring, and obesity is accompanied by an increase in blood leptin levels. The "yellow" mutation at the mouse agouti locus (A(y)) increases blood leptin levels in C57BL preobese pregnant mice without affecting other metabolic characteristics. We investigated the influence of the A(y) mutation or leptin injection at the end of pregnancy in C57BL mice on metabolic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24089373
DOI: 10.1152/ajpregu.00162.2013

Genes

NPY
POMC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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