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Article

Thrombin generation and bleeding in haemophilia A.

Haemophilia : the official journal of the World Federation of Hemophilia - 1 Sept 2009

Brummel-Ziedins K E, Whelihan M F, Gissel M, Mann K G, Rivard G E

Abstract excerpt

Haemophilia A displays phenotypic heterogeneity with respect to clinical severity. The aim of this study was to determine if tissue factor (TF)-initiated thrombin generation profiles in whole blood in the presence of corn trypsin inhibitor (CTI) are predictive of bleeding risk in haemophilia A. We studied factor(F) VIII deficient individuals (11 mild, 4 moderate and 12 severe) with a well-characterized 5-year...

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Identifiers

PMID: 19563500
DOI: 10.1111/j.1365-2516.2009.01994.x
PMCID: PMC3395070

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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