Article
Clinical utility of activated partial thromboplastin time clot waveform analysis and thrombin generation test in the evaluation of bleeding phenotype in Hemophilia A.
Indian journal of pathology & microbiology - 1 Jan 2000
Dave Rutvi G, Geevar Tulasi, Mammen Joy J, Vijayan Ramya, Mahasampath Gowri, Nair Sukesh C
Abstract excerpt
CONTEXT: Hemophilia A is classified as mild, moderate, and severe based on Factor VIII levels (FVIII). Clot-based assays only detect initiation of thrombin generation, hence FVIII levels may not accurately predict the bleeding risk in all hemophilia patients. The entire process of thrombin generation as measured by global hemostasis tests like activated partial thromboplastin time clot waveform analysis (APTT...
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