Article
Patients with moderate hemophilia A and B with a severe bleeding phenotype have an increased burden of disease.
Journal of thrombosis and haemostasis : JTH - 1 Jan 2024
Verhagen Marieke J A, van Balen Erna C, Blijlevens Nicole M A, Coppens Michiel, van Heerde Waander L, Leebeek Frank W G, Rijpma Sanna R, van Vulpen Lize F D, Gouw Samantha C, Schols Saskia E M
Abstract excerpt
BACKGROUND: Patients with moderate hemophilia express varying bleeding phenotypes. OBJECTIVES: To assess the burden of disease in patients with moderate hemophilia and a mild or severe phenotype incorporating the thrombin generation profile. METHODS: This sub-study of the 6th Hemophilia in the Netherlands study, analyzed data of adults with moderate hemophilia A or B. Patient characteristics and information on...
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