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Article

Biological determinants of bleeding in patients with heterozygous factor XI deficiency.

British journal of haematology - 1 Jan 2012

Guéguen Paul, Galinat Hubert, Blouch Marie-Thérèse, Bridey Françoise, Duchemin Jérôme, Le Gal Grégoire, Abgrall Jean-François, Pan-Petesch Brigitte

Abstract excerpt

Bleeding risk is not predictable in patients with factor XI (FXI; F11) deficiency. In this prospective study, our objectives were to determine the biological determinants for bleeding risk in patients with heterozygous FXI deficiency. Patients were classified as either bleeding patients or non-bleeding patients by calculating the bleeding score (BS) described for von Willebrand disease. Primary haemostasis,...

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Identifiers

PMID: 22098495
DOI: 10.1111/j.1365-2141.2011.08945.x

Genes

VWF

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