Article
Common variants in 8q24 are associated with risk for prostate cancer and tumor aggressiveness in men of European ancestry.
The Prostate - 1 Oct 2009
Pal Prodipto, Xi Huifeng, Guha Saurav, Sun Guangyun, Helfand Brian T, Meeks Joshua J, Suarez Brian K, Catalona William J, Deka Ranjan
Abstract excerpt
BACKGROUND: Recent whole genome association studies have independently identified multiple prostate cancer (PC) risk variants on 8q24. We have evaluated association of common variants in this region with PC susceptibility and tumor aggressiveness in a sample of European American men. METHODS: Forty-nine tagging SNPs including three previously reported significant variants (rs1447295, rs6983267, rs16901979) and...
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