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Article

Genetic Polymorphisms and Genetic Risk Scores Contribute to the Risk of Coronary Artery Disease (CAD) in a North Indian Population.

International journal of molecular sciences - 5 Aug 2024

Mastana Sarabjit, Halai Kushni Charisma, Akam Liz, Hunter David John, Singh Puneetpal

Abstract excerpt

Coronary artery disease (CAD) is the leading cause of death in India. Many genetic polymorphisms play a role in regulating oxidative stress, blood pressure and lipid metabolism, contributing to the pathophysiology of CAD. This study examined the association between ten polymorphisms and CAD in the Jat Sikh population from Northern India, also considering polygenic risk scores. This study included 177 CAD cases...

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Identifiers

PMID: 39126122
DOI: 10.3390/ijms25158552
PMCID: PMC11313018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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