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Article

Tissue-specific and neural activity-regulated expression of human BDNF gene in BAC transgenic mice

25 Jun 2009

Abstract excerpt

BACKGROUND: Brain-derived neurotrophic factor (BDNF) is a small secreted protein that has important roles in the developing and adult nervous system. Altered expression or changes in the regulation of the BDNF gene have been implicated in a variety of human nervous system disorders. Although regulation of the rodent BDNF gene has been extensively investigated, in vivo studies regarding the human BDNF gene are...

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PMID: 19555478
DOI: 10.1186/1471-2202-10-68

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