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Article

Neuroligin 2 controls the maturation of GABAergic synapses and information processing in the retina.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 24 Jun 2009

Hoon Mrinalini, Bauer Gabriele, Fritschy Jean-Marc, Moser Tobias, Falkenburger Bjoern H, Varoqueaux Frédérique

Abstract excerpt

In the present study, we investigated the role of Neuroligin 2 (NL2) in synaptic transmission and network function using the mouse retina as a model circuit. We show that NL2 is preferentially located at GABAergic rather than glycinergic or glutamatergic postsynapses. The absence of NL2 from the retina resulted in a severe reduction of GABA(A) receptor clustering, and in subtle alterations of the retinal...

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Identifiers

PMID: 19553444
DOI: 10.1523/JNEUROSCI.0534-09.2009
PMCID: PMC6666037

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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