Article
Modulation of the intestinal microbiota alters colitis-associated colorectal cancer susceptibility.
PloS one - 24 Jun 2009
Uronis Joshua M, Mühlbauer Marcus, Herfarth Hans H, Rubinas Tara C, Jones Gieira S, Jobin Christian
Abstract excerpt
It is well established that the intestinal microbiota plays a key role in the pathogenesis of Crohn's disease (CD) and ulcerative colitis (UC) collectively referred to as inflammatory bowel disease (IBD). Epidemiological studies have provided strong evidence that IBD patients bear increased risk for the development of colorectal cancer (CRC). However, the impact of the microbiota on the development of...
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