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Gut commensal bacteria influence colorectal cancer development by modulating immune response in AOM/DSS-treated mice

16 May 2025

Abstract excerpt

ABSTRACT The gut microbiota has been closely associated with the pathogenesis of colorectal cancer (CRC). However, precise identification of particular microorganisms promoting CRC carcinogenesis, and more importantly those blocking tumor development, has been challenging based on human gut microbiota profiling studies. With a well-established azoxymethane/dextran sodium sulfate induction murine CRC model, we...

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PMID: 40377337
DOI: 10.1128/spectrum.02792-24

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