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Article

NAT2, meat consumption and colorectal cancer incidence: an ecological study among 27 countries.

Cancer causes & control : CCC - 1 Nov 2006

Ognjanovic Simona, Yamamoto Jennifer, Maskarinec Gertraud, Le Marchand Loïc

Abstract excerpt

The polymorphic gene NAT2 is a major determinant of N-acetyltransferase activity and, thus, may be responsible for differences in one's ability to bioactivate heterocyclic amines, a class of procarcinogens in cooked meat. An unusually marked geographic variation in enzyme activity has been described for NAT2. The present study re-examines the international direct correlation reported for meat intake and...

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Source

Identifiers

PMID: 17006723
DOI: 10.1007/s10552-006-0061-3

Genes

NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

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NAT2, meat consumption and colorectal cancer incidence: an ecological study among 27 countries.PMID 17006723Read ↗

Interaction between Red Meat Intake and NAT2 Genotype in Increasing the Risk of Colorectal Cancer in Japanese and African Americans.Semantic proximity Read ↗

Prospective study of NAT1 and NAT2 polymorphisms, tobacco smoking and meat consumption and risk of colorectal cancer.Semantic proximity Read ↗

Prospective study of N‐acetyltransferase‐2 genotypes, meat intake, smoking and risk of colorectal cancerSemantic proximity Read ↗

Red meat intake, NAT2, and risk of colorectal cancer: a pooled analysis of 11 studies.Semantic proximity Read ↗

Meat and heterocyclic amine intake, smoking, NAT1 and NAT2 polymorphisms, and colorectal cancer risk in the multiethnic cohort study.Semantic proximity Read ↗

Effect of NAT1 and NAT2 genetic polymorphisms on colorectal cancer risk associated with exposure to tobacco smoke and meat consumption.Semantic proximity Read ↗

Combined effects of well-done red meat, smoking, and rapid N-acetyltransferase 2 and CYP1A2 phenotypes in increasing colorectal cancer risk.Semantic proximity Read ↗

A prospective study of N-acetyltransferase genotype, red meat intake, and risk of colorectal cancer.Semantic proximity Read ↗

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Polymorphism of the N-acetyltransferase 2 gene, red meat intake, and the susceptibility of hepatocellular carcinoma.Semantic proximity Read ↗

A meta-analysis of the relationship between NAT2 polymorphism and colorectal cancer susceptibility.Semantic proximity Read ↗

Systematic review: diet-gene interactions and the risk of colorectal cancer.Semantic proximity Read ↗

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