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Article

Genetic variation at the perilipin locus is associated with changes in serum free fatty acids and abdominal fat following mild weight loss.

International journal of obesity (2005) - 1 Nov 2006

Jang Y, Kim O Y, Lee J H, Koh S J, Chae J S, Kim J Y, Park S, Cho H, Lee J E, Ordovas J M

Abstract excerpt

OBJECTIVE: Perilipin (PLIN) is a class of protein-coating lipid droplets in adipocytes. We aimed to examine the association between common single-nucleotide polymorphisms (SNPs) at PLIN locus with circulating free fatty acid (FFA) and abdominal fat distribution in response to weight loss. METHODS: Non-diabetic/overweight-obese Koreans (n=177) participated in a 12-week calorie restriction (-300kcal/day) program....

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Source

Identifiers

PMID: 16585946
DOI: 10.1038/sj.ijo.0803312

Genes

PGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Click a neighbor to travelStep 1 · 12 closest

Genetic variation at the perilipin locus is associated with changes in serum free fatty acids and abdominal fat following mild weight loss.PMID 16585946Read ↗

Gender-specific association of a perilipin gene haplotype with obesity risk in a white population.Semantic proximity Read ↗

Intragenic linkage disequilibrium structure of the human perilipin gene (PLIN) and haplotype association with increased obesity risk in a multiethnic Asian population.Semantic proximity Read ↗

A functional variant in the exon 5 of PLIN1 reduces risk of central obesity by possible regulation of lipid storage.Semantic proximity Read ↗

Genetic variation at the perilipin (PLIN) locus is associated with obesity-related phenotypes in White women.Semantic proximity Read ↗

Relationship between perilipin gene polymorphisms and body weight and body composition during weight loss and weight maintenance.Semantic proximity Read ↗

Polymorphism PLIN1 11482 G>A interacts with dietary intake to modulate anthropometric measures and lipid profile in adults with normal-weight obesity syndrome.Semantic proximity Read ↗

Association between three genetic variants of the Perilipin Gene (PLIN) and glucose metabolism: results from a replication study among Chinese adults and a meta-analysis.Semantic proximity Read ↗

Effects of perilipin (PLIN) gene variation on metabolic syndrome risk and weight loss in obese children and adolescents.Semantic proximity Read ↗

Common variations in perilipin gene, central obesity, and risk of type 2 diabetes in US women.Semantic proximity Read ↗

Perilipin gene variation determines higher susceptibility to insulin resistance in Asian women when consuming a high-saturated fat, low-carbohydrate diet.Semantic proximity Read ↗

Obese subjects carrying the 11482G>A polymorphism at the perilipin locus are resistant to weight loss after dietary energy restriction.Semantic proximity Read ↗

Polymorphisms in perilipin gene (PLIN) are not associated with obesity and weight variation in people with high risk of type 2 diabetes.Semantic proximity Read ↗

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