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Article

A functional variant in the exon 5 of PLIN1 reduces risk of central obesity by possible regulation of lipid storage.

Biochemical and biophysical research communications - 24 Jan 2015

Song Weihua, Yu Hui, Lin Yahui, Sun Kai, Zhang Yinhui, Song Yan, Hui Rutai, Chen Jingzhou

Abstract excerpt

PURPOSE: Perilipin coats lipid droplets in adipocytes and steroidogenic cells. Its major role is in the regulation of intracellular lipolysis in adipocytes. Our aim was to examine the association between common variants at the PLIN1 gene and central obesity in unrelated Chinese adults. METHODS: A case-control study was carried out on 869 patients with central obesity and 869 age- and gender-matched individuals...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25529448
DOI: 10.1016/j.bbrc.2014.12.053

Genes

PLIN1

Provenance

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A functional variant in the exon 5 of PLIN1 reduces risk of central obesity by possible regulation of lipid storage.PMID 25529448Read ↗

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