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Article

Knockdown of alpha myosin heavy chain disrupts the cytoskeleton and leads to multiple defects during chick cardiogenesis.

Journal of anatomy - 1 Jun 2009

Rutland Catrin, Warner Louise, Thorpe Aaran, Alibhai Aziza, Robinson Thelma, Shaw Barry, Layfield Robert, Brook J David, Loughna Siobhan

Abstract excerpt

Atrial septal defects are a common congenital heart defect in humans. Although mutations in different genes are now frequently being described, little is known about the processes and mechanisms behind the early stages of atrial septal development. By utilizing morpholino-induced knockdown in the chick we have analysed the role of alpha myosin heavy chain during early cardiogenesis in a temporal manner. Upon...

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Source

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Identifiers

PMID: 19538634
DOI: 10.1111/j.1469-7580.2009.01079.x
PMCID: PMC2705299

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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