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Article

Langerhans cells are critical in the development of atopic dermatitis-like inflammation and symptoms in mice.

Journal of cellular and molecular medicine - 1 Aug 2009

Elentner Andreas, Finke Daniela, Schmuth Matthias, Chappaz Stéphane, Ebner Susanne, Malissen Bernard, Kissenpfennig Adrien, Romani Nikolaus, Dubrac Sandrine

Abstract excerpt

Genetic or vitamin D3-induced overexpression of thymic stromal lymphopoietin (TSLP) by keratinocytes results in an atopic dermatitis (AD)-like inflammatory phenotype in mice echoing the discovery of high TSLP expression in epidermis from AD patients. Although skin dendritic cells (DC) are suspected to be involved in AD, direct evidence of a pathogenetic role for skin DC in TSLP-induced skin inflammation has not...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19538461
DOI: 10.1111/j.1582-4934.2009.00797.x
PMCID: PMC8183941

Genes

TSLP
CCL17
CCL22

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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