Article
Langerhans cells and more: langerin-expressing dendritic cell subsets in the skin.
Immunological reviews - 1 Mar 2010
Romani Nikolaus, Clausen Björn E, Stoitzner Patrizia
Abstract excerpt
Langerhans cells (LCs) are antigen-presenting dendritic cells (DCs) that reside in epithelia. The best studied example is the LC of the epidermis. By electron microscopy, their identifying feature is the unique rod- or tennis racket-shaped Birbeck granule. The phenotypic hallmark is their expression of the C-type lectin receptor langerin/CD207. Langerin, however, is also expressed on a recently discovered...
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