Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

IL-1β induces thymic stromal lymphopoietin and an atopic dermatitis-like phenotype in reconstructed healthy human epidermis.

The Journal of pathology - 1 Jun 2017

Bernard Marine, Carrasco Cédric, Laoubi Léo, Guiraud Béatrice, Rozières Aurore, Goujon Catherine, Duplan Hélène, Bessou-Touya Sandrine, Nicolas Jean-François, Vocanson Marc, Galliano Marie-Florence

Abstract excerpt

Atopic dermatitis (AD) is a common skin inflammatory disease characterized by the production of thymic stromal lymphopoietin (TSLP) and marked TH 2 polarization. Recent studies suggest that IL-1β contributes to the development of AD skin inflammation. Here, we have investigated the impact of IL-1β signalling on the epidermal homeostasis of both healthy subjects and AD patients [with functional filaggrin (FLG)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Monoclonal, Humanized
Share to Dermatitis, Atopic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epidermis

Share to Filaggrin Proteins

Share to Interleukin 1 Receptor Antagonist Protein

Share to Interleukin-1beta

Share to Intermediate Filament Proteins

Share to Thymic Stromal Lymphopoietin

Source

Identifiers

PMID: 28191908
DOI: 10.1002/path.4887

Genes

TSLP
FLG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

IL-1β induces thymic stromal lymphopoietin and an atopic dermatitis-like phenotype in reconstructed healthy human epidermis.PMID 28191908Read ↗

Atopic Dermatitis Beyond the Skin Barrier: Precision Medicine Approaches to Immunological Profiling and Therapeutic InnovationSemantic proximity Read ↗

TSLP is a direct trigger for T cell migration in filaggrin-deficient skin equivalentsSemantic proximity Read ↗

The Keratinocyte as a Crucial Cell in the Predisposition, Onset, Progression, Therapy and Study of the Atopic Dermatitis.Semantic proximity Read ↗

IL-17 Receptor A Maintains and Protects the Skin Barrier To Prevent Allergic Skin Inflammation.Semantic proximity Read ↗

From the morphological to the transcriptomic characterization of a compromised three-dimensional in vitro model mimicking atopic dermatitis.Semantic proximity Read ↗

The atopic march: current insights into skin barrier dysfunction and epithelial cell-derived cytokines.Semantic proximity Read ↗

Spontaneous atopic dermatitis in mice expressing an inducible thymic stromal lymphopoietin transgene specifically in the skinSemantic proximity Read ↗

Langerhans cells and skin immune diseasesSemantic proximity Read ↗

Atopic dermatitis: A tale of two distinct pathomechanisms that make you itch.Semantic proximity Read ↗

Spontaneously Resolved Atopic Dermatitis Shows Melanocyte and Immune Cell Activation Distinct From Healthy Control SkinSemantic proximity Read ↗

Immune-mediated Skin Inflammation is Similar in Severe Atopic Dermatitis Patients With or Without Filaggrin Mutation.Semantic proximity Read ↗

Induction of psoriasis- and atopic dermatitis-like phenotypes in 3D skin equivalents with a fibroblast-derived matrix.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.