Article
Identification of a novel population of Langerin+ dendritic cells.
The Journal of experimental medicine - 24 Dec 2007
Bursch Laura S, Wang Liangchun, Igyarto Botond, Kissenpfennig Adrien, Malissen Bernard, Kaplan Daniel H, Hogquist Kristin A
Abstract excerpt
Langerhans cells (LCs) are antigen-presenting cells that reside in the epidermis of the skin and traffic to lymph nodes (LNs). The general role of these cells in skin immune responses is not clear because distinct models of LC depletion resulted in opposite conclusions about their role in contact hypersensitivity (CHS) responses. While comparing these models, we discovered a novel population of LCs that resides...
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