Article
Mouse Models for Atopic Dermatitis.
Current protocols - 1 Mar 2023
Sakamoto Keiko, Nagao Keisuke
Abstract excerpt
Atopic dermatitis (AD) is a multifactorial disease with underlying barrier disruption and altered microbial flora, resulting in dry skin and eczematous inflammation with persistent pruritis. Mouse models have been heavily used to investigate AD pathophysiology. Among various AD mouse models, AD-like inflammation induced by topical calcipotriol, a vitamin D3 analog referred to as MC903 in experimental settings, is...
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