Article
The association between interferon regulatory factor 6 (IRF6) and nonsyndromic cleft lip with or without cleft palate in a Honduran population.
The Laryngoscope - 1 Sept 2009
Diercks Gillian R, Karnezis Tom T, Kent David T, Flores Carlos, Su Gloria H, Lee Joseph H, Haddad Joseph
Abstract excerpt
OBJECTIVES/HYPOTHESIS: Interferon regulatory factor 6 (IRF6), the gene that causes van der Woude syndrome (VWS), is a candidate gene for nonsyndromic cleft lip with or without cleft palate (NSCLP) because a number of studies have supported an association between NSCLP and single nucleotide polymorphisms (SNPs) in IRF6 in several populations. This project investigated the contribution of IRF6 to NSCLP in the...
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