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Article

Association between IRF6 and nonsyndromic cleft lip with or without cleft palate in four populations.

Genetics in medicine : official journal of the American College of Medical Genetics - 1 Apr 2007

Park Ji Wan, McIntosh Iain, Hetmanski Jacqueline B, Jabs Ethylin Wang, Vander Kolk Craig A, Wu-Chou Yah-Huei, Chen Philip K, Chong Samuel S, Yeow Vincent, Jee Sun Ha, Park Beyoung Yun, Fallin M Daniele, Ingersoll Roxann, Scott Alan F, Beaty Terri H

Abstract excerpt

PURPOSE: The interferon regulatory factor 6 (IRF6), the gene that causes van der Woude syndrome has been shown to be associated with nonsyndromic cleft lip with or without palate in several populations. This study aimed to confirm the contribution of IRF6 to cleft lip with or without palate risk in additional Asian populations. METHODS: A set of 13 single nucleotide polymorphisms was tested for association with...

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Identifiers

PMID: 17438386
DOI: 10.1097/gim.0b013e3180423cca
PMCID: PMC2846512

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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