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Genetic risk factors for nonsyndromic cleft lip with or without cleft palate in a Mesoamerican population: Evidence for <i>IRF6</i> and variants at 8q24 and 10q25

17 Jun 2010

Abstract excerpt

INTRODUCTION: Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is one of the most common of all birth defects. NSCL/P has a multifactorial etiology that includes both genetic and environmental factors. The IRF6 gene and three further susceptibility loci at 8q24, 10q25, and 17q22, which were identified by a recent genome-wide association scan (GWAS), are confirmed genetic risk factors for NSCL/P in...

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PMID: 20564431
DOI: 10.1002/bdra.20689

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Genetic risk factors for nonsyndromic cleft lip with or without cleft palate in a Mesoamerican population: Evidence for <i>IRF6</i> and variants at 8q24 and 10q25PMID 20564431Read ↗

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