Article
Personality traits and the R668Q polymorphism located in the MMP-9 gene.
Behavioural brain research - 1 Mar 2012
Suchankova Petra, Pettersson Robert, Nordenström Kajsa, Holm Göran, Ekman Agneta
Abstract excerpt
Matrix metalloproteinases (MMPs) are enzymes involved in degradation of proteins in the extracellular matrix and have been shown to contribute to neuroinflammation by several mechanisms such as blood-brain barrier breakdown. Among the MMPs, MMP-9 (gelatinase B) has been suggested to be of relevance also for synaptic and behavioural plasticity. In order to explore the role of MMP-9 for mental functions a...
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