Article
Specific matrix metalloproteinase 9 (MMP-9) haplotype affect the circulating MMP-9 levels in women with migraine.
Journal of neuroimmunology - 15 Nov 2012
Martins-Oliveira Alisson, Gonçalves Flavia M, Speciali Jose G, Fontana Vanessa, Izidoro-Toledo Tatiane C, Belo Vanessa A, Dach Fabiola, Tanus-Santos Jose E
Abstract excerpt
We investigated whether three relevant polymorphisms (C-1562T, microsatellite -90(CA)(14-24), and Q279R) in the MMP-9 gene, or MMP-9 haplotypes, are associated with migraine and affect MMP-9 and tissue inhibitor of MMPs (TIMP)-1 levels in patients with migraine. We studied 102 healthy women (controls) and 187 women with migraine (141 without aura - MWA, and 46 with aura - MA). Patients with MWA had higher plasma...
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